At HormoneSynergy®, we believe aging is inevitable - but how you age is optional. Optimal health and longevity go beyond simply preventing disease; they’re about achieving vibrant physical, mental, and emotional well-being at every stage of life.
Under the leadership of Dr. Kathryn Retzler, a nationally recognized physician with 25+ years of experience, HormoneSynergy® delivers evidence-based preventive longevity medicine for patients in Portland & Lake Oswego—and for those seeking care nationwide.
Our focus is simple: detect risk early, improve function, and extend healthspan through physician-led, measurement-driven care. We combine advanced diagnostics, lifestyle medicine, and evidence-based therapies—including hormone optimization when appropriate—to help restore energy, mental clarity, and metabolic resilience.
We are not alternative. We don’t sell immortality. We’re not a protocol clinic. And we’re not a supplement store with a stethoscope.
We help patients reduce cardiometabolic risk and improve measurable markers of metabolic health—often dramatically—using data, accountability, and real medicine.
Our concierge services include:
- Preventive & Precision Medicine – Extending Healthspan with science-driven strategies to help slow the effects of aging.
- Bioidentical Hormone Replacement Therapy (BHRT) – including testosterone therapy for men and women.
- Functional Medicine & Lifestyle Optimization – personalized nutrition, supplements, and fitness plans.
- Cognitive Health & Preventive Care – targeted cutting-edge therapies for brain and metabolic health.
- Preventive Cardiology - Advanced Cardiovascular Testing, Cleerly® Testing, and Carotid Artery Ultersound with health assessments designed for proactive prevention and peace of mind.
- Weight Loss - GLP-1 Medically Supervised Weightloss
With a focus on affordable, science-based care and a dedication to helping you look, feel, and live your best, HormoneSynergy® is the trusted choice for achieving optimal health and longevity in Portland and Lake Oswego Oregon and beyond.
Dr. Kathryn Retzler
Physician. Educator. Author. Consultant
"I believe many people settle for a negative definition of aging. I do not accept that aging means 'falling apart on schedule'. I have a high standard for my physical, mental and spiritual health, improving every year. I hold the same vision for my patients.
Preventive Longevity and Precision Medicine
At HormoneSynergy®, we serve individuals who want more than traditional “disease care” or symptom management. Our concierge Longevity Medicine and Age Management clinic combines the principles of personalized precision and functional medicine to help you achieve optimal health and vitality.
Rather than treating symptoms alone, we focus on the underlying causes of aging and health concerns, using advanced diagnostics, evidence-based therapies, and lifestyle optimization strategies tailored to your unique physiology. By integrating the latest research in hormone optimization, functional medicine, and preventive health, we create a comprehensive plan designed to help you look, feel, and live your best—at every stage of life.
HormoneSynergy® / RetzlerRx® Weight Loss for Longevity Program
The HormoneSynergy® / RetzlerRx® Weight Loss for Life Program is a medically supervised, science-driven weight loss program designed to improve body composition, metabolic health, and longevity.
This comprehensive approach combines advanced DEXA body composition analysis, personalized functional medicine coaching, and targeted nutritional supplements with GLP-1 weight loss medications such as semaglutide or tirzepatide. The goal is to help you achieve sustainable weight loss, improved metabolic balance, and long-term health optimization—not just temporary results.
Cleerly® Testing - A New Standard for Cardiovascular Care
Cleerly® Heart Health Analysis uses a clinically proven, AI-powered digital care platform with Coronary Computed Tomography Angiography (CCTA) to help Dr. Kathryn Retzler precisely detect and evaluate atherosclerosis (heart and vascular disease) at its earliest stages.
This advanced technology provides comprehensive visualization of coronary plaque, including both calcified and non-calcified deposits, while assessing the severity of stenosis to stage and track heart disease progression over time.
By leveraging AI-enabled CCTA analysis, Cleerly® offers faster, more accurate, and highly personalized heart health insights—empowering you with a proactive, precision-based cardiovascular care plan designed to improve long-term outcomes and optimize longevity.
DEXA (DXA) Bone Density plus Full Body and Visceral Fat Analysis
Our Hologic® DXA Bone Density and Body Composition Analysis offers a cutting-edge, non-invasive diagnostic scan designed to provide precise insights into bone health, muscle mass, and visceral fat levels.
The DXA Bone Density Scan uses advanced X-ray technology to accurately measure bone mineral density, helping to assess your risk for osteoporosis, fractures, and age-related bone loss. This quick, painless procedure delivers reliable results that support personalized health and longevity strategies tailored to your unique needs.
Our Whole Body and Visceral Fat Analysis takes body composition assessment a step further—measuring the fat stored around critical organs, known as visceral fat, which has been linked to cardiovascular disease and metabolic disorders. By combining bone health evaluation with a comprehensive analysis of muscle and fat distribution, we give you a clear, data-driven picture of your overall health and wellness.
Carotid Artery Ultrasound using Vasolabs® with Butterfly Ultrasound Technology
Vasolabs® Heart Disease Screenings offer an affordable, convenient, and non-invasive way to detect early signs of heart disease—with no physician referral required. Using state-of-the-art vascular ultrasound technology, Vasolabs® delivers fast, accurate, and pain-free heart health assessments designed for proactive prevention and peace of mind.
Key benefits of Vasolabs® Heart Screenings include:
- No Referrals Needed – Schedule your screening directly—no waiting or paperwork delays.
- Advanced Ultrasound Technology – Detect early signs of heart disease with the latest imaging innovations.
- Non-Invasive & Comfortable – No wires, treadmills, or needles required; just a quick, stress-free test.
- Fast Results – Receive your easy-to-read report within 48 hours via email.
- Optional Clinician Consultation – Review your results with a healthcare provider if desired.
- Quick & Affordable – The test takes just 15 minutes and costs only $249.
Take control of your heart health today. Call 503-230-7990 to schedule your Vasolabs® Heart Disease Screening.
Preventive Cardiology
Cardiovascular disease remains the leading cause of death in the United States—claiming more than 800,000 lives each year. Every 25 seconds, someone suffers a heart attack, and every minute, someone dies from cardiovascular disease. For survivors, the financial burden is substantial: average out-of-pocket costs for stroke or heart attack range from $25,000–$30,000 annually after insurance, increasing by $100,000 or more if surgery is required.
At HormoneSynergy®, Dr. Kathryn Retzler specializes in Preventive Cardiology and has completed two preventive cardiology fellowships through the American Academy of Anti-Aging Medicine with Mark Houston, MD—bringing a proactive, evidence-based approach to:
- Identifying cardiovascular risk early through advanced imaging and lab testing
- Implementing personalized prevention strategies using lifestyle, nutrition, and medical interventions
- Reducing heart attack and stroke risk while supporting long-term cardiovascular health and longevity
Take charge of your heart health before symptoms appear—because prevention saves lives and protects your future.
Bioidentical Hormone Replacement
Humans are unique because we spend a significant portion of our lives beyond our reproductive years. For many, aging accelerates in the mid to late 40s as hormone levels naturally decline and reproductive ability decreases. Since hormones influence nearly every system in the body, this decline often affects energy, metabolism, muscle mass, bone health, mood, memory, and sexual wellness.
At HormoneSynergy®, we offer Bioidentical Hormone Replacement Therapy (BHRT) using human-identical hormones designed to restore optimal balance. Our personalized hormone optimization programs may help support:
- Energy and vitality for active, healthy aging
- Metabolism, muscle tone, and fat loss for better body composition
- Bone strength and joint health to reduce age-related decline
- Mood, memory, and sexual wellness for overall quality of life
- Skin elasticity and healthy appearance for youthful vibrance
With a functional medicine approach focused on the root causes of aging, our hormone replacement programs are tailored to your unique health needs, helping you feel and live your best at every stage of life.
Testosterone Replacement Therapy
Testosterone Therapy for both men and women plays a vital role in supporting metabolic health, sexual wellness, athletic performance, and overall quality of life. As testosterone levels naturally decline with age, many individuals experience changes in energy, mood, muscle mass, and cognitive function that can affect long-term health and well-being.
At HormoneSynergy®, we offer personalized testosterone optimization programs designed to help support:
- Metabolic health and healthy body composition
- Sexual function and libido for men and women
- Athletic performance and muscle strength for active lifestyles
- Mood stability and mental clarity for emotional and cognitive wellness
- Heart health and diabetes prevention through balanced hormone support
Using a functional and integrative medicine approach, we tailor testosterone therapy to your unique health goals, helping restore vitality and optimize longevity at every stage of life.
I’ve been Dr. Retzler’s patient for nearly 24 years, and I consider myself very fortunate to have found her. With her guidance and bioidentical hormone treatment, I’ve eased through menopause enjoying vibrant health and well-being. I feel wonderful!*
Judith Bernards
HormoneSynergy® Clinic & RetzlerRx® specialize in longevity medicine, GLP-1 weight loss, Integrative medicine, and bioidentical hormone therapy in Portland / Lake Oswego OR.
Physician-formulated nutritional supplements, shipped USA nationwide.
Non concierge services include carotid artery ultrasound, DEXA / DXA Bone Density Scans, SECA Body Composition testing and our GLP-1 Weight Loss for Longevity™ program.